CH3CONHNH2

CH3CONHNH2 is an organic compound known as acetohydrazide or N-acetylhydrazine. It is an acylhydrazide derived from acetic acid and hydrazine, with the chemical formula C2H6N2O. Structurally, it consists of a methylcarbonyl group linked to a hydrazine nitrogen, giving the fragment CH3-CO-NH-NH2.

Synthesis and reactions: Acetohydrazide is typically prepared by the acylation of hydrazine with acetylating agents such as acetyl chloride or acetic anhydride. The resulting compound serves as a versatile building block in organic synthesis, enabling transformations that form a variety of hydrazide derivatives and heterocycles. It can participate in condensation and cyclization reactions that lead to pyrazoles, triazoles, and related structures, making it useful in the development of pharmaceuticals and agrochemicals.

Properties: Acetohydrazide is a small, polar molecule. It is soluble in water and in various polar organic solvents and is used as a reagent and intermediate in synthesis. Like other hydrazide species, it is reactive at the N–N and N–C bonds and can be sensitive to strong oxidizers or extreme conditions. Proper handling and storage in appropriate conditions are recommended.

Applications: The compound is employed as a synthetic intermediate to access a range of hydrazide derivatives and heterocyclic compounds. It serves as a convenient starting point for the preparation of more complex molecules in pharmaceutical, agricultural, and materials chemistry contexts.

Safety: Hydrazine-derived compounds, including acetohydrazide, can be toxic and potentially hazardous. They should be handled with appropriate safety precautions in a well-ventilated area, using personal protective equipment, and stored away from oxidizers.