Bromaceton

Bromaceton, also known as alpha-bromopropanone or 1-bromo-2-propanone, is a halogenated ketone with the chemical formula C3H5BrO. Its structure features an acetone backbone with a bromine atom substituted at the methyl group adjacent to the carbonyl, giving CH3-CO-CH2Br.

Physically, bromaceton is described as a volatile, colorless liquid with a distinct, sharp odor. It is more soluble in organic solvents than in water and is flammable. Handling requires appropriate ventilation and standard chemical hygiene practices to minimize exposure to vapors or skin contact.

Preparation typically involves alpha-bromination of acetone under controlled conditions, followed by purification, usually by distillation. As a reactive alpha-halo ketone, bromaceton can participate in various nucleophilic substitutions and condensation reactions, making it a useful interim building block in organic synthesis.

In practical use, bromaceton serves as a chemical intermediate in the preparation of other halogenated ketones and related compounds. Its applications are mainly in laboratory-scale synthesis and industrial settings where such intermediates are required. Because of its reactivity and potential misuse, its availability is often regulated in industrial and laboratory contexts.

Safety and handling: bromaceton is corrosive and can cause irritation to skin, eyes, and the respiratory tract. It should be used in a well-ventilated fume hood with appropriate personal protective equipment, and stored away from heat sources and incompatible materials.

Regulatory status: in several countries, bromaceton is listed as a controlled or regulated chemical due to its potential use in illicit synthesis, and its distribution and handling may be subject to specific controls.