Bocprotecting
Bocprotecting refers to the chemical process of introducing a tert-butyloxycarbonyl (Boc) group to a molecule, typically to protect a functional group during a chemical reaction. The Boc group is a common protecting group for amines and, less frequently, for alcohols and thiols. Its primary purpose is to temporarily mask the reactivity of these functional groups, preventing them from participating in unwanted side reactions.
The Boc group is typically installed using di-tert-butyl dicarbonate (Boc anhydride) in the presence of a base,
The deprotection of the Boc group is usually achieved under acidic conditions. Strong acids like trifluoroacetic