Betanaphthylamine

Betanaphthylamine, also known as 2-naphthylamine or BNA, is an organic compound with the chemical formula C10H7NH2. It is an isomer of naphthylamine, differing in the position of the amino group on the naphthalene ring. Historically, betanaphthylamine was used in the production of azo dyes and as an antioxidant.

However, betanaphthylamine is a potent human carcinogen. It has been definitively linked to an increased risk of bladder cancer. Due to its severe health risks, its production and use have been severely restricted or banned in many countries. Exposure can occur through inhalation, skin absorption, or ingestion.

The carcinogenic properties of betanaphthylamine are attributed to its metabolic activation within the body, leading to the formation of reactive intermediates that can damage DNA. This damage, if not repaired, can lead to mutations and the development of cancer. Consequently, stringent safety measures and personal protective equipment are essential when handling any materials that might contain betanaphthylamine, even in trace amounts. Its historical use means that contaminated sites may still pose a risk.