Asetilsalisilat

Asetilsalisilat, also known as acetylsalicylic acid, is a widely used medication belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is commonly recognized by its brand name, Aspirin. Its primary uses include relieving pain, reducing fever, and decreasing inflammation. It is also utilized for its antiplatelet properties, which help prevent blood clots, making it a crucial medication in the prevention of heart attacks and strokes in certain individuals.

The mechanism of action of asetilsalisilat involves the irreversible inhibition of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. By inhibiting these enzymes, it reduces the production of prostaglandins, which are signaling molecules that play a role in pain, fever, and inflammation. The antiplatelet effect is due to the inhibition of COX-1 in platelets, thereby reducing thromboxane A2 synthesis.

Asetilsalisilat is available in various forms, including tablets, capsules, and effervescent tablets, and can be taken orally. Common side effects include gastrointestinal irritation, such as nausea, vomiting, and heartburn. More serious side effects can include stomach ulcers, bleeding, and allergic reactions. It is important to use asetilsalisilat as directed by a healthcare professional and to be aware of potential interactions with other medications. It is generally not recommended for children and teenagers due to the risk of Reye's syndrome.