ArgAsp

ArgAsp is a chemical compound with the molecular formula C16H19N3O4. It is a derivative of arginine, an amino acid, and is commonly used in the field of proteomics as a labeling reagent. ArgAsp is characterized by its ability to react with primary amines, such as those found in proteins, forming stable amide bonds. This property makes it useful for protein labeling, purification, and identification.

The synthesis of ArgAsp involves the reaction of arginine with aspartic acid, followed by the formation of an amide bond between the two amino acids. The resulting compound is then purified to obtain ArgAsp in its pure form.

ArgAsp is widely used in various biological and biochemical research applications. It is employed in protein labeling techniques, such as isobaric tags for relative and absolute quantitation (iTRAQ), which allows for the simultaneous quantification of multiple proteins in complex mixtures. Additionally, ArgAsp is used in protein purification processes, where it can be conjugated to affinity matrices to selectively capture target proteins.

In summary, ArgAsp is a versatile chemical compound derived from arginine and aspartic acid. Its ability to react with primary amines makes it a valuable tool in proteomics for protein labeling, purification, and identification. Its applications in biological and biochemical research continue to expand, contributing to our understanding of protein function and interactions.