Angiopoietinerna
Angiopoietins are a family of proteins that play a crucial role in the development and maintenance of blood vessels. They are essential for angiogenesis, the process by which new blood vessels form from existing ones. The angiopoietin family consists of several members, with angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2) being the most extensively studied.
Ang1 primarily acts to stabilize mature blood vessels. It binds to the Tie2 receptor on endothelial cells,
In contrast, Ang2 often functions as a modulator of Ang1 activity, and its role can be context-dependent.
Angiopoietins are involved in a variety of physiological and pathological processes, including inflammation, tissue repair, and