AlphaFold2s
AlphaFold2 is a deep learning-based protein structure prediction method developed by DeepMind, a subsidiary of Alphabet Inc. It was released in 2020 and has since become a significant tool in the field of structural biology. AlphaFold2 uses a neural network to predict the three-dimensional structure of a protein from its amino acid sequence. The model is trained on a large dataset of known protein structures, allowing it to learn the relationships between sequences and structures. AlphaFold2 has demonstrated high accuracy in predicting protein structures, often outperforming traditional methods. It has been used to predict the structures of thousands of proteins, including those that are difficult to study experimentally. AlphaFold2's predictions have been validated through experimental techniques such as X-ray crystallography and cryo-electron microscopy. The method has also been applied to predict the structures of proteins involved in diseases, providing insights into potential drug targets. AlphaFold2's success has highlighted the potential of artificial intelligence in biological research and has sparked interest in developing similar tools for other biological systems.