67Dihydroxycoumarin

6,7-Dihydroxycoumarin, also known as 6,7-dihydroxy-2H-1-benzopyran-2-one, is an organic compound that represents a dihydroxy derivative of coumarin. In this molecule, two hydroxyl groups are attached at the 6- and 7-positions of the benzopyranone framework, giving a catechol-like substitution on the ring fused to the lactone.

Its chemical formula is C9H6O4 and its molecular weight is about 178.12 g/mol. The presence of adjacent phenolic OH groups makes the compound relatively polar and capable of forming intramolecular hydrogen bonds. The compound absorbs ultraviolet light similarly to other coumarins, with substituent effects influencing the absorption spectrum.

6,7-Dihydroxycoumarin is primarily encountered as a synthetic intermediate and reference compound in studies of hydroxylated coumarins. It is not commonly reported as a natural product, though related dihydroxy derivatives can arise in plant metabolism or be prepared by hydroxylation of parent coumarins through chemical or enzymatic methods.

In research settings, dihydroxycoumarins are explored for antioxidant activity, potential metal chelation, and use as building blocks in dyes, pharmaceuticals, or polymer chemistry. The adjacent phenolic groups may undergo oxidation to o-quinones, enabling further chemical transformations.

Safety and handling follow standard protocols for phenolic compounds. Specific toxicity and hazard data for 6,7-dihydroxycoumarin should be consulted from safety resources.