2thiophenecarboxaldehyde

2-thiophenecarboxaldehyde, also known as 2-formylthiophene, is an organic compound with the chemical formula C5H4OS. It is a derivative of thiophene, a five-membered heterocyclic aromatic ring containing one sulfur atom, with an aldehyde group attached at the second position. This compound typically appears as a colorless to pale yellow liquid with a characteristic odor.

It is synthesized through various methods, often involving the Vilsmeier-Haack reaction on thiophene. The aldehyde functional group makes it a versatile building block in organic synthesis. It readily undergoes reactions characteristic of aldehydes, such as oxidation to the corresponding carboxylic acid, reduction to the alcohol, and nucleophilic addition reactions.

2-thiophenecarboxaldehyde finds applications as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. Its thiophene ring system imparts specific electronic and structural properties that can be exploited in the design of biologically active molecules or materials with optical properties. It is a commercially available reagent used in research and industrial chemical processes.