2methoxyphenethylamine

2-methoxyphenethylamine, also known as o-methoxyphenethylamine or 2-MeO-PEA, is an organic compound in the phenethylamine class. It consists of a benzene ring bearing a methoxy group at the 2-position and a two-carbon side chain ending in an amino group (–CH2–CH2–NH2). The molecular formula is C9H13NO, with a molecular weight of about 151.2 g/mol.

As an ortho-substituted mono-methoxyphenethylamine, it is part of a small family of related compounds including the 3- and 4-methoxy isomers. The presence of the methoxy group increases the ring’s polarity relative to unsubstituted phenethylamine and can influence the compound’s electronic properties and potential interactions with biological systems. In common with many simple phenethylamines, the amine is basic and can form protonated salts.

Occurrence and potential uses are not well documented in peer‑reviewed literature. The compound is typically discussed as a chemical intermediate or research chemical rather than a marketed pharmaceutical or consumer product. It may be cited in discussions of structure–activity relationships within the broader class of methoxyphenethylamines, but specific pharmacological or therapeutic data for the 2‑methoxy isomer are limited.

Safety and regulation: As with other amine-containing organic compounds, handling should follow standard laboratory precautions. There is no widely recognized medical use for this compound, and regulatory status varies by country. Some jurisdictions regulate mono‑substituted phenethylamines under broader controlled‑substances or chemical‑weapon precursor laws, so local regulations should be consulted if exposure or possession is anticipated.