1Phenylpropan2ol

1-phenylpropan-2-ol is an organic compound with the chemical formula C9H12O. It is a colorless liquid with a mild, floral odor, often used as a fragrance component in perfumery and cosmetics. Structurally, it belongs to the class of secondary alcohols, characterized by a hydroxyl group (-OH) attached to a secondary carbon atom within a propanol backbone, which is further substituted with a phenyl group (C6H5).

This compound is synthesized primarily through the reduction of 1-phenylpropan-2-one (also known as acetophenone) using reducing agents such as sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4). It can also be produced via the hydroboration-oxidation of allylbenzene or through enzymatic processes involving alcohol dehydrogenases.

In perfumery, 1-phenylpropan-2-ol is valued for its ability to contribute to floral, fruity, and slightly woody notes, often found in compositions such as jasmine, lily, and certain citrus fragrances. Due to its pleasant aroma, it is also incorporated into soaps, detergents, and personal care products. However, its use in food applications is limited due to regulatory restrictions in many countries, as it is not generally recognized as safe (GRAS) for consumption.

From a chemical perspective, 1-phenylpropan-2-ol exhibits typical properties of secondary alcohols, including reactivity with oxidizing agents to form ketones and participation in esterification reactions. It is soluble in organic solvents but has limited solubility in water. The compound’s stability is generally good under normal conditions, though prolonged exposure to air or light may lead to gradual oxidation.

Safety considerations include its potential to cause skin irritation in concentrated forms, and proper handling, such as wearing gloves and ensuring adequate ventilation, is recommended during synthesis or handling. As with many fragrance ingredients, its use in commercial products is subject to regulatory guidelines to ensure consumer safety.