vortexmixers

A vortex mixer is a laboratory device used to mix small volumes of liquids in tubes or microplates by creating a vortex. It consists of a motor-driven platform that oscillates or rotates to impart rapid circulating motion to the liquid, producing vortices that mix contents efficiently and rapidly. Vortex mixing is widely used for resuspending pellets, dissolving reagents, and homogenizing samples in molecular biology, biochemistry, and clinical laboratories.

Most common type is the orbital vortex mixer, in which the platform itself moves in a circular orbit while the tube or vessel remains stationary. This motion is generated at adjustable speeds from a few hundred to several thousand revolutions per minute, often with a built-in timer. Many models accept accessories such as adapters or cups to fit microcentrifuge tubes, PCR tubes, cryovials, or microplates, enabling simultaneous mixing of multiple tubes or wells. In addition to standard bench-top units, plate vortex mixers are designed to mix whole microplates or deep-well plates and may offer multiple mixing heads or specialized clamps.

Operational considerations include choosing an appropriate speed and duration for the sample type, avoiding overfilling and splashing, and using compatible vessel closures to minimize aerosol formation. Safety practices emphasize working with sealed or capped vessels for volatile or hazardous liquids, and routine cleaning to prevent cross-contamination.