vereseerumi

Veriseerumi, sometimes written vereseerumi, is the clear, pale-yellow liquid component that remains in blood after coagulation. It is produced when a blood sample is allowed to clot and then is separated by centrifugation from the clotted material. Unlike plasma, veriseerumi does not contain fibrinogen or other clotting factors, which are consumed during coagulation. This distinction between serum and plasma is important for laboratory testing and sample handling.

Veriseerumi comprises mostly water, but also contains electrolytes, proteins such as albumin and immunoglobulins, hormones, metabolites, enzymes, and antibodies. Because the clotting factors are removed, some lab tests are performed on serum rather than plasma; certain analytes may respond differently in serum due to the absence of fibrinogen or other clotting proteins.

Clinical use: Serum is widely used for diagnostic chemistry, immunology, and serology tests, including antibody detection and many metabolic panels. It is commonly collected in non-anticoagulant tubes and is preferred in some assays to avoid anticoagulant interference. In research, serum is also used as a growth supplement for cell culture (for example, fetal bovine serum or human serum).

Handling and storage: After collection, allow clotting, centrifuge, and aliquot the serum. Store at 2–8 C for short-term use or -20 C or colder for long-term storage; repeated freeze–thaw cycles should be minimized to preserve component integrity. Good laboratory practice includes avoiding hemolysis and documenting the sample’s origin and handling conditions.