tyrosiinitargetteja
Tyrosiinitargetteja refers to compounds that inhibit or modulate the activity of tyrosine kinases. Tyrosine kinases are enzymes that play a crucial role in cellular signaling pathways by catalyzing the transfer of a phosphate group from ATP to tyrosine residues on target proteins. This phosphorylation event can trigger a cascade of downstream effects, influencing cell growth, differentiation, survival, and metabolism.
Dysregulation of tyrosine kinase activity is implicated in the development and progression of various diseases, particularly
Examples of tyrosine kinases that are targets for therapeutic intervention include epidermal growth factor receptor (EGFR),