trombocitaadhézió

Trombocitaadhézió refers to the process by which platelets, also known as thrombocytes, stick to non-platelet surfaces. This is a crucial initial step in hemostasis, the process the body uses to stop bleeding. When a blood vessel is injured, exposing components like collagen, platelets in the bloodstream are activated. This activation leads to a change in the platelet's shape and the expression of specific adhesion molecules on their surface, such as glycoprotein Ib (GPIb) and glycoprotein IIb/IIIa (GPIIb/IIIa). These molecules can then bind to molecules present on the damaged vessel wall, primarily von Willebrand factor (vWF) and collagen. This initial adhesion allows platelets to tether to the site of injury, even under the high shear stress of blood flow. Without proper trombocitaadhézió, platelets would simply be washed away from the injury site, preventing the formation of a platelet plug and subsequent blood clot. Disruptions in this process can lead to bleeding disorders.