tanteiden

Tanteiden, also known as Tanteiden Syndrome, is a rare genetic disorder characterized by the absence of the second and third toes on both feet. It is caused by a mutation in the SHOX gene, which is responsible for the development of the lower limbs. Individuals with Tanteiden Syndrome typically have a normal lifespan and do not experience any significant health issues related to the condition. The syndrome is inherited in an autosomal dominant pattern, meaning that a person only needs to inherit one mutated copy of the SHOX gene from a parent to develop the condition. Tanteiden Syndrome is estimated to affect approximately one in 100,000 people worldwide. The condition was first described in 1974 by a Dutch pediatrician, and since then, several cases have been reported in the medical literature. Despite its rarity, Tanteiden Syndrome is an important example of how genetic mutations can lead to unique and often subtle physical differences in humans.