stereoisomerisaatioon
Stereoisomerisation is the chemical process by which a molecule changes its stereoisomeric form without changing the connectivity of its atoms. Stereoisomers are compounds that have the same sequence of bonded atoms but differ in the three-dimensional arrangement of those atoms. The process can involve interconversion of enantiomers (mirror-image isomers) and/or diastereomers, such as geometric isomers around a double bond (cis/trans) or around cyclic systems (atropisomers).
Interconversion can occur through various mechanisms. Photochemical or thermal energy can promote rotation about a carbon–carbon
The ability to control stereoisomerisation is important in synthesis and pharmaceuticals, where the biological activity of
Examples include cis–trans isomerisation of alkenes under light or heat and racemization at stereogenic centers under