seleniumsulfid

Selenium sulfide is an inorganic compound with the formula SeS2. It is one of the selenium sulfides and appears as a yellow to orange crystalline solid. The substance is best known for its use in topical products to treat dandruff and certain scalp conditions.

Industrial production and occurrence: Selenium sulfide is primarily prepared by the direct combination of elemental selenium and sulfur at elevated temperatures. It is not typically found as a natural mineral and is produced synthetically for commercial use. The solid can exist in more than one crystalline form (polymorphs), with its exact structure depending on preparation conditions.

Physical and chemical properties: Selenium sulfide is sparingly soluble in water and more soluble in certain nonpolar organic solvents. It is relatively stable under normal conditions but can decompose upon heating or prolonged exposure to light. In practice, the compound is often used in formulated preparations where stabilizers and carriers control release and skin compatibility.

Applications and mechanism: The principal application of selenium sulfide is in anti-dandruff shampoos and scalp treatments. In these products, it exhibits antifungal activity, particularly against Malassezia species linked to dandruff and seborrheic dermatitis. The exact mechanism is not fully understood but is believed to involve disruption of fungal cell function and growth.

Safety and handling: Selenium sulfide can be irritating to skin and eyes and may be harmful if ingested or inhaled. Products containing SeS2 should be used according to label directions, and prolonged exposure or improper handling should be avoided.