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salicyl

Salicyl is not a single chemical compound but a stem used in the names of various organic compounds that derive from the salicylic framework. The root salicyl- appears in terms such as salicylaldehyde, salicylamide, and salicylates, and it is derived from the historical association of salicylic compounds with willow bark. The core motif behind the salicyl- family is the ortho-hydroxybenzoic acid skeleton, a benzene ring bearing a hydroxyl group adjacent to a carboxyl group.

In nature, salicylates occur in plants, and salicylic acid functions as a plant signaling molecule involved

Safety and regulatory notes are important when handling salicyl derivatives. High-dose salicylates can cause gastrointestinal irritation

in
defense
responses
and
systemic
acquired
resistance.
In
medicine
and
chemistry,
salicylates
and
their
derivatives
are
valued
for
a
range
of
properties.
Salicylic
acid
itself
is
used
topically
as
a
keratolytic
agent
to
treat
acne
and
certain
skin
conditions,
and
it
serves
as
a
key
building
block
in
the
synthesis
of
other
compounds.
Acetylation
of
salicylic
acid
yields
acetylsalicylic
acid,
commonly
known
as
aspirin,
a
widely
used
analgesic,
anti-inflammatory,
and
antipyretic
drug.
Derivatives
such
as
salicylaldehyde
and
salicylamides
are
important
intermediates
in
pharmaceutical
and
fragrance
chemistry.
and
other
adverse
effects;
aspirin
use
in
children
with
viral
infections
has
been
associated
with
a
risk
of
Reye’s
syndrome,
leading
to
precautionary
guidelines.
Overall,
salicyl-
compounds
are
a
broad
and
historically
significant
class
in
both
organic
chemistry
and
pharmacology.