rsmZ
RsmZ is a small regulatory RNA (sRNA) found in several Gram-negative bacteria, most notably in Pseudomonas species. It belongs to the RsmY/RsmZ family of non-coding RNAs and functions as a post-transcriptional regulator by binding RNA-binding proteins of the CsrA/RsmA family. By sequestering RsmA, RsmZ reduces the ability of RsmA to repress target mRNAs, thereby promoting translation of downstream genes.
RsmZ expression is controlled by the GacS/GacA two-component system. In response to environmental cues, GacA activates
The RsmZ molecule typically contains multiple stem-loop structures and conserved GGA sequence motifs that contribute to
RsmZ functions in a regulatory network with other sRNAs and factors, and its activity can influence pathogenic