reprotoxicant

A reprotoxicant is a substance that can negatively affect sexual function and fertility in adult males and females. It can also be harmful to the development of the offspring. This includes effects on libido, fertility, and both the male and female reproductive systems. Additionally, reprotoxicants can impact pregnancy outcomes, causing adverse effects on the developing fetus or child, such as birth defects, developmental delays, or functional deficits. The World Health Organization categorizes reprotoxicants as substances that cause adverse effects on sexual function and fertility, and on development of the offspring.

Exposure to reprotoxicants can occur through various routes, including inhalation, ingestion, and skin contact. Common sources of exposure include certain pesticides, industrial chemicals, heavy metals, and some pharmaceuticals. The impact of a reprotoxicant depends on the dose, duration, and timing of exposure, as well as individual susceptibility. For instance, exposure during critical periods of fetal development can lead to irreversible harm.

Identifying and managing reprotoxicants is important for public health. Regulatory agencies establish exposure limits and guidelines to minimize the risks associated with these substances. Research continues to identify new reprotoxicants and understand their mechanisms of action to better protect reproductive health and the development of future generations.