rdr
RdR stands for RNA-dependent RNA polymerase, an enzyme that copies RNA from an RNA template. It is a central component of the replication machinery for RNA viruses, enabling genome amplification without a DNA intermediate. While RdRp is the more commonly used abbreviation in modern literature, some sources still use RdR.
RdR enzymes catalyze the synthesis of RNA in a template-directed manner, typically using nucleoside triphosphates and
RdRs are encoded by nearly all RNA viruses, including positive-sense viruses like picornaviruses, flaviviruses, and coronaviruses;
Because RdRps are essential for viral replication and absent in host DNA-directed polymerases, they are important
Note: the term RdR is sometimes used interchangeably with RdRp, but readers should consider context to avoid