preklininen
Preklininen is the Finnish term for the preclinical stage of biomedical research, the phase that precedes testing in humans. It encompasses laboratory experiments and animal studies intended to characterize a candidate’s biological activity, safety, and pharmacokinetic properties before any clinical trials can be initiated.
Typical activities in preclinical research include in vitro assays to assess target engagement and efficacy, pharmacokinetics
Regulatory context: Preclinical data are used to determine starting doses for human trials and to support applications
Limitations: Although preclinical studies strive to predict human outcomes, they cannot fully replicate human physiology, and