polihexanid

Polihexanide, also known as polyhexamethylene biguanide (PHMB), is a polymer used as a disinfectant and antiseptic. It is a cationic biocide that works by disrupting the cell membranes of microorganisms. PHMB is effective against a broad spectrum of bacteria, fungi, and some viruses.

It is commonly found in various consumer products, including contact lens solutions, wound dressings, swimming pool sanitizers, and as a preservative in cosmetics and personal care items. Its efficacy and relatively low toxicity make it a popular choice for applications where microbial control is important.

PHMB functions by binding to negatively charged components of microbial cell surfaces. This interaction leads to an increase in cell membrane permeability, causing leakage of essential intracellular components and ultimately cell death. Its polymeric nature contributes to its persistent antimicrobial activity.

In medical settings, PHMB is utilized in antiseptic solutions and impregnated dressings for wound care to prevent and treat infections. Its use in swimming pools helps maintain water hygiene by controlling algae and bacteria. Due to its disinfectant properties, it can also be found in some household cleaning products. While generally considered safe for its intended uses, potential for skin irritation exists in some individuals.