pledomain
pledomain refers to a specific protein domain found in various organisms. This domain is characterized by a conserved amino acid sequence and a three-dimensional structure that confers a particular function. Proteins containing the pledomain are often involved in cellular processes such as signal transduction, gene regulation, and protein-protein interactions. The name "pledomain" itself is derived from the observation that it is frequently found in proteins associated with pleiotropic effects, meaning those proteins influence multiple traits or functions.
Research on pledomain-containing proteins has identified their roles in diverse biological pathways. For instance, some pledomain