phenazocine

Phenazocine is a synthetic opioid analgesic. It belongs to the benzomorphan class of compounds and is structurally related to other opioids like pentazocine and cyclazocine. Phenazocine was developed in the mid-1950s and has been used clinically for pain management.

Its mechanism of action involves binding to opioid receptors in the central nervous system, primarily the mu-opioid receptor, where it acts as an agonist. This interaction modulates the perception of pain. Phenazocine is considered a potent analgesic, often used for moderate to severe pain. It can be administered orally, intramuscularly, or intravenously.

Like other opioids, phenazocine carries risks of side effects, including respiratory depression, constipation, nausea, vomiting, and sedation. Physical dependence and addiction are also potential concerns with prolonged use. Its use is typically reserved for situations where other analgesics are insufficient or contraindicated. Due to its potential for abuse, phenazocine is a controlled substance in many countries. Medical supervision is generally required for its prescription and use.