parabromocumene

Parabromocumene, also known as 4-bromocumene or 1-bromo-4-isopropylbenzene, is an organobromine compound with the chemical formula C9H11Br. It is a derivative of cumene (isopropylbenzene) where a bromine atom is substituted at the para position of the benzene ring. At room temperature, it typically appears as a colorless liquid.

This compound finds its primary use as an intermediate in organic synthesis. The bromine atom can be readily displaced in various reactions, allowing for the introduction of other functional groups onto the cumene structure. It can participate in reactions such as Grignard reagent formation, palladium-catalyzed cross-coupling reactions like Suzuki or Heck couplings, and nucleophilic aromatic substitution under specific conditions. These synthetic pathways enable the creation of more complex molecules used in pharmaceuticals, agrochemicals, and material science. Parabromocumene is generally prepared through the bromination of cumene. It is important to handle parabromocumene with appropriate safety precautions as organobromine compounds can have varying degrees of toxicity and irritancy.