papaverin
Papaverin is an alkaloid derived from the opium poppy, Papaver somniferum. It is a vasodilator, meaning it widens blood vessels, which can help lower blood pressure and improve blood flow. Papaverin is often used in the treatment of peripheral artery disease, Raynaud's phenomenon, and other conditions characterized by poor circulation. It works by inhibiting the action of calcium ions, which are necessary for muscle contraction in blood vessel walls. This inhibition leads to relaxation of the smooth muscles in the blood vessels, thereby increasing their diameter and improving blood flow. Papaverin is typically administered orally or intravenously, and its effects can last for several hours. It is generally considered safe and well-tolerated, but like any medication, it can cause side effects such as dizziness, headache, and nausea. As with any drug, papaverin should be used under the guidance of a healthcare professional to ensure it is appropriate for the individual's specific condition and medical history.