palokuolemia

Palpable jaundice, also known as palokuolemia, is a condition characterized by a visible or palpable yellowish discoloration of the skin, particularly on the knees and elbows. It is a symptom of severe liver disease or severe hemolysis, which can cause the accumulation of bilirubin in the skin.

Palpable jaundice is often accompanied by other symptoms such as fatigue, weakness, and loss of appetite. In severe cases, it can also cause darkened urine and a yellowish discoloration of other tissues, including the whites of the eyes.

In patients with liver disease, palpable jaundice is typically a sign that the disease is progressing to a severe stage. It is often associated with other markers of liver failure, such as elevated liver enzymes and decreased liver function tests.

In cases of hemolysis, palpable jaundice is caused by the breakdown of red blood cells, leading to the accumulation of bilirubin in the skin. This type of jaundice is often seen in patients with blood disorders, such as sickle cell anemia or glucose-6-phosphate dehydrogenase deficiency.

The diagnosis of palpable jaundice is typically made through clinical examination and diagnostic tests, such as liver function tests and bilirubin levels. Treatment of palpable jaundice depends on the underlying cause and may involve addressing the underlying condition, such as liver failure or hemolysis, through medications or other interventions.