pFBA
pFBA stands for primal-dual interior-point method for flux balance analysis. It is a computational method used in systems biology to determine the optimal metabolic flux distribution in a biological system. Flux balance analysis (FBA) itself is a technique that models cellular metabolism as a network of biochemical reactions and uses optimization principles to predict the flow of metabolites through this network under specific conditions.
pFBA is an enhancement to standard FBA. Standard FBA typically aims to maximize or minimize a single
The "primal-dual interior-point" aspect refers to the specific type of mathematical algorithm used to solve the