p53independent
p53independent refers to cellular processes or molecular pathways that function independently of the tumor suppressor protein p53. The p53 protein, often called the "guardian of the genome," plays a critical role in responding to cellular stress, such as DNA damage, by inducing cell cycle arrest, apoptosis, or senescence. This prevents the proliferation of damaged cells, thereby reducing the risk of cancer.
Therefore, "p53independent" describes mechanisms that bypass or do not rely on p53's regulatory functions to achieve
Research into p53independent pathways is significant for understanding cancer development and devising therapeutic strategies. Identifying these