p18INK4c
p18INK4c, also known as CDKN2C, is a protein encoded by the CDKN2C gene. It belongs to the INK4 family of cyclin-dependent kinase inhibitors. These inhibitors play a critical role in regulating the cell cycle, specifically by preventing the activation of cyclin-dependent kinases (CDKs) that are responsible for driving the cell through its different phases.
The p18INK4c protein primarily targets CDK4 and CDK6. By binding to these CDKs, p18INK4c inhibits their association
The expression of p18INK4c is tightly regulated and can be influenced by various cellular signals. Its role