notchI
notchI, also known as Notch homolog 1, is a gene that plays a crucial role in cell differentiation and development. It is part of the Notch signaling pathway, a highly conserved intercellular communication mechanism found in multicellular organisms. This pathway is essential for a wide range of developmental processes, including embryonic patterning, cell fate determination, and tissue homeostasis.
The NotchI gene encodes a transmembrane receptor protein that, upon binding to its ligands on neighboring cells,
Dysregulation of NotchI signaling has been implicated in various diseases, particularly cancers. In many types of