nonnicotine

Nonnicotine is a descriptive term used to indicate the absence of nicotine in a product, sample, or substance. It is not a formal chemical name or a standardized category in pharmacology, but it appears in consumer labeling and scientific discourse to differentiate nicotine-free materials from those containing nicotine.

In consumer products, nonnicotine substances include nicotine-free e-liquids, nicotine-free gums or lozenges, and some vaping devices marketed as nonnicotine or nicotine-free. Such products may use propylene glycol and vegetable glycerin as carriers, along with flavorings and additives, but do not deliver nicotine.

In research and regulation, analysts may test for nicotine content and report nonnicotine to indicate zero nicotine; labeling requirements vary by country. Some jurisdictions require explicit "nicotine-free" labeling rather than the ambiguous "nonnicotine."

Health and safety considerations: Absence of nicotine reduces the potential for addiction and cardiovascular stimulation associated with nicotine, but nonnicotine products can still carry health risks from other ingredients, including solvents, flavorings, or contaminants. The long-term effects of regular exposure to some nonnicotine aerosols or solvents are not fully known.

Related terms: Non-nicotinic refers to actions or receptors not related to nicotine; nornicotine is a separate nicotine alkaloid found in tobacco and is distinct from "nonnicotine."