neuropeptidek
Neuropeptide K (NPK) is a neuropeptide derived from the neurotensin (NT) precursor protein in vertebrates. It is produced by proteolytic processing of prepro-neurotensin and is released together with neurotensin from NT-expressing neurons in the brain and gut. It is detected in various brain regions and peripheral tissues such as the gastrointestinal tract.
NPK acts as a signaling molecule by interacting with neurotensin receptors. It functions as a ligand within
Physiological roles attributed to neuropeptide K include modulation of nociception, locomotor and behavioral responses, feeding and
In research contexts, NPK is studied as part of the neurotensinergic system and as a potential biomarker