multimerization
Multimerization refers to the process by which multiple individual subunits (monomers) assemble into a larger, discrete complex called a multimer. Multimers range from dimers (two subunits) to higher-order oligomers and sometimes polymers. The subunits may be identical (homo-multimers) or different (heteromultimers).
Multimerization is driven mainly by noncovalent interactions such as hydrophobic contacts, hydrogen bonds, and electrostatic interactions,
Biological roles: Many proteins function as multimers, and the assembly can influence activity, stability, and regulation.
Methods and implications: Multimerization can be studied by structural and biophysical methods, including cryo-electron microscopy, X-ray
Terminology: The term oligomer describes assemblies of several subunits; dimers, trimers, and tetramers are common forms.