mucosaalapú
Mucosaalapú approaches refer to strategies that target mucosal surfaces, the moist linings of the body such as the gastrointestinal, respiratory, and reproductive tracts, as well as the oral cavity. The term is used in pharmacology, vaccinology, and biomaterials to describe formulations and devices designed to interact with mucus and mucosal tissues rather than relying solely on systemic routes.
Mucosal surfaces serve as barriers and immunological sites. They provide a large surface area and access to
To address these barriers, researchers use mucoadhesive polymers, permeation enhancers, and carrier systems such as nanoparticles,
Applications include mucosaalapú vaccines that induce mucosal IgA responses and systemic immunity, mucosaalapú drug delivery for
Advantages include non-invasive administration, potential for rapid onset, and improved patient acceptance. Limitations involve formulation stability,
Research focuses on materials, delivery devices, and regulatory pathways to advance mucosaalapú strategies while ensuring safety