moksifloksatsiin

Moksifloksatsiin is a synthetic fluoroquinolone antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes required for bacterial DNA replication, transcription, repair, and recombination. This ultimately leads to bacterial cell death.

Commonly prescribed for respiratory tract infections such as pneumonia and bronchitis, moksifloksatsiin is also effective against infections of the skin and soft tissues, and intra-abdominal infections. It is available in oral and intravenous formulations. The spectrum of activity includes many Gram-positive and Gram-negative bacteria, as well as atypical pathogens like Mycoplasma and Chlamydia.

Like all antibiotics, moksifloksatsiin can cause side effects. These can range from mild gastrointestinal issues like nausea and diarrhea to more serious adverse events. Potential serious side effects include tendonitis and tendon rupture, peripheral neuropathy, central nervous system effects such as dizziness and confusion, and QT interval prolongation which can lead to arrhythmias. Therefore, it is important to use moksifloksatsiin under the guidance of a healthcare professional. Its use may be contraindicated in individuals with a history of tendon disorders related to fluoroquinolone administration or those with known hypersensitivity to the drug.