missequencing
Missequencing refers to errors that occur during the process of DNA sequencing. These errors can manifest in several ways, most commonly as incorrect base calls, where a nucleotide base (adenine, guanine, cytosine, or thymine) is misidentified. Other types of missequencing include insertion or deletion errors, where extra bases are added or bases are missing from the sequence, leading to frameshift mutations in downstream analyses.
The causes of missequencing are varied and can arise at multiple stages of the sequencing workflow. These
The impact of missequencing depends heavily on the application. In research, missequencing can lead to incorrect