microsyringes

A microsyringe is a specialized type of syringe designed for dispensing extremely small volumes of liquids, typically in the microliter or nanoliter range. They are characterized by a fine-gauge needle and a precisely calibrated plunger, allowing for accurate measurement and delivery of minute quantities. The barrel of a microsyringe is usually made of glass or plastic and has markings that indicate the volume dispensed.

Microsyringes are essential tools in various scientific and medical fields. In analytical chemistry, they are used for sample injection into chromatographic instruments like gas chromatographs (GC) and high-performance liquid chromatographs (HPLC). Their precision is crucial for obtaining reliable analytical results. In biology and medicine, microsyringes are employed for microinjection, a technique used to introduce substances into cells or to perform in vitro fertilization. They are also utilized in research involving small animal models for precise drug delivery.

The operation of a microsyringe involves drawing the liquid into the barrel by pulling back the plunger and then expelling it by pushing the plunger forward. Due to the small volumes involved, factors like air bubbles, surface tension, and the viscosity of the liquid can significantly affect accuracy. Therefore, careful technique and proper handling are important when using microsyringes. Maintenance often involves thorough cleaning to prevent contamination and ensure continued precision.