mentholiin

Menthol is a cyclic terpene alcohol known for its characteristic minty aroma and cooling sensation. It is naturally found in the oils of peppermint, corn mint, and other mint plants. Menthol exists as several stereoisomers, with l-menthol being the most common and responsible for the physiological cooling effect. This cooling is achieved through its interaction with TRPM8 receptors in the skin and mucous membranes, which are cold-sensitive ion channels.

Commercially, menthol is synthesized or extracted from mint oils. It is widely used in various products due to its sensory properties and mild anesthetic effects. Common applications include toothpaste, mouthwash, chewing gum, confectionery, and cigarettes, where it adds a refreshing flavor and aroma. In pharmaceuticals and over-the-counter remedies, menthol is incorporated into lozenges, cough drops, nasal inhalers, topical analgesics, and balms to relieve symptoms of sore throat, cough, congestion, and minor muscle pain. Its cooling effect can provide a soothing sensation and a perceived reduction in discomfort. While generally considered safe, high concentrations of menthol can cause skin irritation or allergic reactions in some individuals.