mastcelactivatie
Mast cell activation refers to the process by which mast cells release various potent chemical mediators. These mediators include histamine, proteases, cytokines, and prostaglandins. Mast cells are a type of immune cell found in connective tissues throughout the body, particularly near blood vessels, nerves, and in the skin, lungs, and digestive tract. They play a crucial role in allergic reactions and defense against pathogens, but their overactivity can lead to a range of symptoms.
The activation of mast cells can be triggered by a variety of stimuli. In allergic reactions, this
When mast cells degranulate, the released mediators cause a variety of effects in the surrounding tissues.
Disorders characterized by inappropriate or excessive mast cell activation are known as mast cell activation disorders.