mRNASpleißreaktion
The mRNASpleißreaktion, often referred to as mRNA splicing in English, is a crucial post-transcriptional modification process in eukaryotic cells. It involves the removal of non-coding sequences, known as introns, from a precursor messenger RNA (pre-mRNA) molecule and the joining of the coding sequences, called exons, together. This process is essential for the production of functional mRNA that can be translated into proteins.
The spliceosome, a large and dynamic molecular machine composed of small nuclear ribonucleoproteins (snRNPs) and numerous
Through a series of coordinated RNA-protein interactions and conformational changes within the spliceosome, the intron is