liposomer
Liposomer, also commonly referred to as a liposome, is a nanoscale or microscale vesicle formed when amphiphilic lipids assemble into closed bilayers in an aqueous environment. The structure consists of one or more phospholipid bilayers that enclose an aqueous core, enabling encapsulation of hydrophilic substances in the interior and incorporation of lipophilic compounds within the bilayer itself. Liposomers range in size from about 20 nanometers to several micrometers and are categorized as small unilamellar vesicles, large unilamellar vesicles, or multilamellar vesicles based on lamellarity.
Preparation methods include thin-film hydration, reverse-phase evaporation, ethanol or isopropanol injection, detergent dialysis, and microfluidic assembly.
Applications are broad in biomedicine and cosmetics. In drug delivery, liposomers can improve solubility, protect labile
Challenges include physical instability (leakage, fusion), oxidation of lipids, storage requirements, batch variability, and occasional immune