kortikosteroidale
Kortikosteroalele are a class of steroid hormones produced by the adrenal cortex and synthetic analogues used as medicines for their anti-inflammatory and immunosuppressive properties. They are grouped into glucocorticoids, which influence metabolism and immune responses, and mineralocorticoids, which regulate electrolyte and water balance. Common therapeutic glucocorticoids include prednisone/prednisolone, methylprednisolone, dexamethasone, and budesonide or fluticasone for local effects; common mineralocorticoids include fludrocortisone for replacement therapy.
Mechanism: Corticosteroids act by binding to intracellular receptors that alter gene transcription, reducing production of pro-inflammatory
Medicinal uses: They are employed to treat many inflammatory and autoimmune conditions (asthma and COPD, eczema
Administration and dosing: Corticosteroids can be given orally, intravenously, intramuscularly, inhaled, topical, or rectal. The lowest
Adverse effects and safety considerations: Short-term use may cause mood changes, increased appetite, and sleep disturbances;