kolekaliferoli

Cholecalciferol, also known as vitamin D3, is a fat-soluble vitamin that plays a crucial role in calcium and phosphorus absorption in the body. It is one of two forms of vitamin D, the other being ergocalciferol (vitamin D2). Cholecalciferol is naturally produced in the skin when it is exposed to ultraviolet B (UVB) radiation from sunlight. It can also be obtained from certain animal-based foods and fortified products.

Once synthesized or ingested, cholecalciferol is transported to the liver and kidneys, where it undergoes metabolic activation to its biologically active form, calcitriol. Calcitriol is essential for maintaining healthy bone density, preventing rickets in children and osteomalacia in adults, and supporting immune function. Deficiency in vitamin D can lead to a range of health issues.

Dietary sources of cholecalciferol include fatty fish like salmon, mackerel, and sardines, as well as egg yolks and fortified dairy products, cereals, and orange juice. Sunlight exposure is a primary source for many individuals, but factors such as latitude, time of day, season, skin pigmentation, and sunscreen use can affect its production. Supplementation is often recommended, particularly for those with limited sun exposure or inadequate dietary intake.