kodonanticodonparene

kodonanticodonparene is a coined term used to describe the codon–anticodon pairing that underlies the decoding of the genetic code during translation. In this view, information encoded in messenger RNA codons is read by transfer RNA anticodons in a ribosome-driven process, with the pairing arranged antiparallel: an mRNA codon, read 5' to 3', aligns with a tRNA anticodon read 3' to 5'. Base pairing follows Watson–Crick rules, with occasional wobble at the third codon position allowing some tRNAs to recognize multiple codons.

Mechanism: Each tRNA carries a specific amino acid determined by aminoacyl-tRNA synthetases. The anticodon of the tRNA recognizes the codon in the ribosomal A site, ensuring the correct amino acid is added to the growing polypeptide. Anticodon loop modifications, such as inosine at the wobble position, expand pairing possibilities and contribute to the code’s redundancy and flexibility.

Significance: kodonanticodonparene emphasizes how codon usage, tRNA abundance, and anticodon chemistry influence translation speed and accuracy. The degeneracy of the genetic code arises in part from wobble pairing and the existence of multiple codons for a single amino acid, coupled with selective tRNA availability.

Origins and usage: The term kodonanticodonparene is not standard in the scientific literature; it appears mainly in educational or speculative contexts as a mnemonic for codon–anticodon interaction. In mainstream genetics, these concepts are described as codon–anticodon pairing or codon recognition by tRNA.