ionotrooppinen
Ionotrooppinen is an adjective used in the field of pharmacology to describe a class of drugs that affect the strength and duration of heart contractions by altering the movement of ions across cell membranes. These drugs are commonly used to treat heart failure and other cardiovascular conditions. Ionotrooppinen agents work by either increasing the influx of calcium ions into the heart muscle cells, which strengthens the contractions, or by blocking the efflux of potassium ions, which prolongs the duration of the contractions. Examples of ionotrooppinen drugs include digitalis, dobutamine, and milrinone. These medications are typically administered intravenously and their effects are closely monitored to avoid potential side effects such as arrhythmias, electrolyte imbalances, and toxicity. The use of ionotrooppinen drugs is an important aspect of modern cardiovascular pharmacotherapy, helping to improve symptoms and quality of life for patients with heart conditions.