intralesionale

Intralesionale is an Italian medical term used as an adjective to describe procedures or phenomena that occur within a lesion. The closest English equivalent is intralesional, referring to therapy delivered directly inside a lesion.

In practice, intralesionale approaches are used in several fields. In dermatology, corticosteroids or other agents may be injected directly into skin lesions such as inflammatory nodules, keloids, or warts to reduce activity or size. In oncology, localized injections into a tumor or lesion may be used for palliative or diagnostic purposes, often when systemic treatment is unsuitable or unnecessary. The term also appears in other branches of medicine where treatment targets a lesion without affecting surrounding tissue.

Etymology and usage: the word is formed from intra- (within) and lesione (lesion) with the Italian adjectival suffix -ale. While intralesionale accurately conveys the concept, it is predominantly found in Italian-language publications; English texts typically use intralesional or intra-lesional therapy.

See also: intralesional, intralesional therapy, localized treatment. References: Italian medical dictionaries and dermatology/oncology texts discuss intralesionale in corresponding Italian usage.